| Protein Name | GATA binding protein 6 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 14465 |
| Gene Symbol | Gata6 |
| UniProt | Q61169 (GATA6_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
46
Total Number of Articles : 42 |
Description |
GATA binding protein 6 |
| Gene Summary |
Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in gene expression; heart contraction; and sinoatrial node development. Acts upstream of or within several processes, including animal organ development; cardiac muscle hypertrophy in response to stress; and endodermal cell fate determination. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and heart. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple); congenital heart disease (multiple); and pancreatic hypoplasia-diabetes-congenital heart disease syndrome. Orthologous to human GATA6 (GATA binding protein 6). [provided by Alliance of Genome Resources, Apr 2022] |
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