| Protein Name | histone deacetylase 8 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 70315 |
| Gene Symbol | Hdac8 |
| UniProt | Q8VH37 (HDAC8_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
22
Total Number of Articles : 22 |
Description |
histone deacetylase 8 |
| Gene Summary |
Predicted to enable chromatin binding activity; heat shock protein binding activity; and histone deacetylase activity. Predicted to be involved in several processes, including histone deacetylation; negative regulation of macromolecule metabolic process; and regulation of chromosome organization. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of histone deacetylase complex. Is expressed in several structures, including 2-cell stage embryo; brain; embryo ectoderm; foregut; and retina. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 5 and Wilson-Turner syndrome. Orthologous to human HDAC8 (histone deacetylase 8). [provided by Alliance of Genome Resources, Apr 2022] |
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