Protein Name transthyretin
Organism Rattus norvegicus
Gene ID 24856
Gene Symbol

Ttr

UniProt P02767 (TTHY_RAT)
Relationships Total Number of functionally related compound(s) : 107
Total Number of Articles : 97
Description

transthyretin

Gene Summary

Enables hormone binding activity. Predicted to be involved in negative regulation of glomerular filtration; purine nucleobase metabolic process; and retinoid metabolic process. Located in extracellular space. Part of protein-containing complex. Biomarker of brain ischemia and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyloidosis; carpal tunnel syndrome 1; dystransthyretinemic hyperthyroxinemia; and transthyretin amyloidosis. Orthologous to human TTR (transthyretin). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • transthyretin
  • prealbumin, amyloidosis type I
  • Lr1
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Properties