CPRiL

Flt1

Fms related receptor tyrosine kinase 1

Enables ATP binding activity; growth factor binding activity; and vascular endothelial growth factor receptor activity. Involved in several processes, including liver regeneration; negative regulation of vascular endothelial growth factor production; and positive regulation of cell population proliferation. Located in extracellular space. Used to study corneal neovascularization. Biomarker of breast cancer; liver cirrhosis; myocardial infarction; retinal disease (multiple); and vascular dementia. Human ortholog(s) of this gene implicated in Kuhnt-Junius degeneration; bronchopulmonary dysplasia; diabetic retinopathy; and pre-eclampsia. Orthologous to human FLT1 (fms related receptor tyrosine kinase 1). [provided by Alliance of Genome Resources, Jul 2025]

• vascular endothelial growth factor receptor 1
• FMS-like tyrosine kinase 1
• Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
tyrosine-protein kinase receptor FLT
vascular endothelial growth factor receptor 1-like
vascular endothelial growth factor/vascular permeability factor receptor
FLT-1
VEGFR-1