Protein Name dopamine receptor D5
Organism Rattus norvegicus
Gene ID 25195
Gene Symbol

Drd5

UniProt P25115 (DRD5_RAT)
Relationships Total Number of functionally related compound(s) : 32
Total Number of Articles : 32
Description

dopamine receptor D5

Gene Summary

Enables G-protein alpha-subunit binding activity and dopamine neurotransmitter receptor activity. Involved in several processes, including adenylate cyclase-activating dopamine receptor signaling pathway; negative regulation of protein kinase activity; and visual learning. Acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway. Located in several cellular components, including brush border membrane; dendritic spine; and neuronal cell body. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and blepharospasm. Orthologous to human DRD5 (dopamine receptor D5). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • D(1B) dopamine receptor
  • d(5) dopamine receptor
  • dopamine D5 receptor
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Properties