Protein Name zinc finger MIZ-type containing 1
Organism Homo sapiens
Gene ID 57178
Gene Symbol

ZMIZ1

UniProt Q9ULJ6 (ZMIZ1_HUMAN), A0A024QZN6 (A0A024QZN6_HUMAN), A0JLS3 (A0JLS3_HUMAN)
Relationships Total Number of functionally related compound(s) : 14
Total Number of Articles : 12
Description

zinc finger MIZ-type containing 1

Gene Summary

This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]

synonyms
  • zinc finger MIZ domain-containing protein 1
  • retinoic acid induced 17
  • zinc finger-containing, Miz1, PIAS-like protein on chromosome 10
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Properties