Protein Name SMAD family member 6
Organism Homo sapiens
Gene ID 4091
Gene Symbol

SMAD6

UniProt O43541 (SMAD6_HUMAN)
Relationships Total Number of functionally related compound(s) : 38
Total Number of Articles : 29
Description

SMAD family member 6

Gene Summary

The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.[provided by RefSeq, Sep 2014]

synonyms
  • mothers against decapentaplegic homolog 6
  • MAD homolog 6
  • SMAD, mothers against DPP homolog 6
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Properties