| Protein Name | estrogen receptor 2b |
|---|---|
| Organism | Danio rerio |
| Gene ID | 317733 |
| Gene Symbol | esr2b |
| UniProt | Q5PR29 (Q5PR29_DANRE), B8JJL3 (B8JJL3_DANRE), B8JJL4 (B8JJL4_DANRE) |
| Relationships |
Total Number of functionally related compound(s) :
14
Total Number of Articles : 11 |
Description |
estrogen receptor 2b |
| Gene Summary |
Enables estradiol binding activity; nuclear estrogen receptor activity; and steroid hormone binding activity. Involved in sex determination. Acts upstream of or within embryonic cranial skeleton morphogenesis; response to estrogen; and swimming behavior. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including forebrain; head; liver; male organism; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); bone disease (multiple); hypospadias; and neurodegenerative disease (multiple). Orthologous to human ESR2 (estrogen receptor 2). [provided by Alliance of Genome Resources, Jul 2025] |
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