| Protein Name | CD247 molecule |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 919 |
| Gene Symbol | CD247 |
| UniProt | P20963 (CD3Z_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
105
Total Number of Articles : 171 |
Description |
CD247 molecule |
| Gene Summary |
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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