Protein Name BRCA1 associated RING domain 1
Organism Mus musculus
Gene ID 12021
Gene Symbol

Bard1

UniProt O70445 (BARD1_MOUSE)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 5
Description

BRCA1 associated RING domain 1

Gene Summary

Predicted to enable RNA binding activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of protein export from nucleus; protein K6-linked ubiquitination; and regulation of apoptotic process. Located in nucleus. Is expressed in central nervous system; genitourinary system; limb; and spleen. Used to study breast cancer. Human ortholog(s) of this gene implicated in breast cancer and ovarian cancer. Orthologous to human BARD1 (BRCA1 associated RING domain 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • BRCA1-associated RING domain protein 1
  • BARD-1
  • RING-type E3 ubiquitin transferase BARD1
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Properties