Protein Name purinergic receptor P2X 4
Organism Homo sapiens
Gene ID 5025
Gene Symbol

P2RX4

UniProt Q99571 (P2RX4_HUMAN)
Relationships Total Number of functionally related compound(s) : 129
Total Number of Articles : 165
Description

purinergic receptor P2X 4

Gene Summary

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]

synonyms
  • P2X purinoceptor 4
  • ATP receptor
  • ATP-gated cation channel protein
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Properties