| Protein Name | cytochrome b-245 alpha chain |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 79129 |
| Gene Symbol | Cyba |
| UniProt | Q62737 (CY24A_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
145
Total Number of Articles : 168 |
Description |
cytochrome b-245 alpha chain |
| Gene Summary |
Contributes to superoxide-generating NAD(P)H oxidase activity. Involved in several processes, including cellular response to L-glutamine; cellular response to gamma radiation; and positive regulation of cell population proliferation. Located in several cellular components, including focal adhesion; perinuclear endoplasmic reticulum; and stress fiber. Part of NADPH oxidase complex. Used to study hypertension and pulmonary hypertension. Biomarker of diabetic retinopathy; end stage renal disease; hypertension; and myocardial infarction. Human ortholog(s) of this gene implicated in artery disease (multiple); asthma; chronic obstructive pulmonary disease; and phagocyte bactericidal dysfunction (multiple). Orthologous to human CYBA (cytochrome b-245 alpha chain). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
|
| Properties | |