Protein Name | lysine demethylase 4B |
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Organism | Homo sapiens |
Gene ID | 23030 |
Gene Symbol | KDM4B |
UniProt | O94953 (KDM4B_HUMAN), F5GX28 (F5GX28_HUMAN), A0A0C4DFL8 (A0A0C4DFL8_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
37
Total Number of Articles : 37 |
Description |
lysine demethylase 4B |
Gene Summary |
Enables histone H3-methyl-lysine-36 demethylase activity and histone H3-methyl-lysine-9 demethylase activity. Involved in histone H3-K36 demethylation and histone H3-K9 demethylation. Located in cytosol and nucleoplasm. Implicated in autosomal dominant non-syndromic intellectual disability; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Biomarker of several diseases, including alopecia areata; lung cancer; medulloblastoma; prostate cancer; and stomach cancer. [provided by Alliance of Genome Resources, Apr 2022] |
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Properties | |