Protein Name potassium channel, subfamily K, member 2
Organism Mus musculus
Gene ID 16526
Gene Symbol

Kcnk2

UniProt P97438 (KCNK2_MOUSE), Q6P6P9 (Q6P6P9_MOUSE), A0A0A6YXK1 (A0A0A6YXK1_MOUSE)
Relationships Total Number of functionally related compound(s) : 54
Total Number of Articles : 57
Description

potassium channel, subfamily K, member 2

Gene Summary

Enables channel activity; identical protein binding activity; and protein heterodimerization activity. Involved in several processes, including chloride transmembrane transport; glutamate secretion; and neuronal action potential. Acts upstream of or within G protein-coupled receptor signaling pathway; potassium ion transport; and regulation of membrane potential. Located in astrocyte projection; dendrite; and plasma membrane. Part of voltage-gated potassium channel complex. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including brain; early conceptus; limb; olfactory epithelium; and secondary oocyte. Orthologous to human KCNK2 (potassium two pore domain channel subfamily K member 2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • potassium channel subfamily K member 2
  • TREK-1 K(+) channel subunit
  • outward rectifying potassium channel protein TREK-1
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Properties