| Protein Name | nuclear respiratory factor 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 18181 |
| Gene Symbol | Nrf1 |
| UniProt | Q9WU00 (NRF1_MOUSE), G3XA39 (G3XA39_MOUSE), E9Q7X0 (E9Q7X0_MOUSE), Q3UXF4 (Q3UXF4_MOUSE), Q99K73 (Q99K73_MOUSE), Q3UYQ3 (Q3UYQ3_MOUSE), Q8C4C0 (Q8C4C0_MOUSE), Q8CAV3 (Q8CAV3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
95
Total Number of Articles : 98 |
Description |
nuclear respiratory factor 1 |
| Gene Summary |
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Acts upstream of or within mitochondrion organization. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; connective tissue; genitourinary system; skeleton; and telencephalon. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to human NRF1 (nuclear respiratory factor 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |