| Protein Name | interferon regulatory factor 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24508 |
| Gene Symbol | Irf1 |
| UniProt | P23570 (IRF1_RAT), Q6DGG4 (Q6DGG4_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
32
Total Number of Articles : 31 |
Description |
interferon regulatory factor 1 |
| Gene Summary |
Enables sequence-specific DNA binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to exogenous dsRNA; and regulation of primary metabolic process. Predicted to be located in chromatin and cytoplasm. Predicted to be active in nucleus. Used to study endometrial adenocarcinoma. Biomarker of allergic conjunctivitis; lung disease; respiratory syncytial virus infectious disease; and ureteral obstruction. Human ortholog(s) of this gene implicated in asthma; immunodeficiency 117; lung cancer (multiple); smallpox; and stomach cancer (multiple). Orthologous to human IRF1 (interferon regulatory factor 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |