Protein Name ER lumen protein-retaining receptor erd-2.1
Organism Caenorhabditis elegans
Gene ID 181228
Gene Symbol

erd-2.1

UniProt -
Relationships Total Number of functionally related compound(s) : 1
Total Number of Articles : 1
Description

ER lumen protein-retaining receptor erd-2.1

Gene Summary

Predicted to enable ER retention sequence binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in cis-Golgi network and endoplasmic reticulum. Is expressed in several structures, including enteric muscle; head mesodermal cell; hermaphrodite distal tip cell; hypodermis; and nervous system. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 21. Orthologous to several human genes including KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1) and KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • ER lumen protein-retaining receptor erd-2.1
  • CELE_F09B9.3
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Properties