Protein Name TNF receptor superfamily member 13B
Organism Homo sapiens
Gene ID 23495
Gene Symbol

TNFRSF13B

UniProt O14836 (TR13B_HUMAN), Q4ACX1 (Q4ACX1_HUMAN)
Relationships Total Number of functionally related compound(s) : 35
Total Number of Articles : 29
Description

TNF receptor superfamily member 13B

Gene Summary

The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

synonyms
  • tumor necrosis factor receptor superfamily member 13B
  • transmembrane activator and CAML interactor
  • tumor necrosis factor receptor 13B
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Properties