| Protein Name | G protein-coupled bile acid receptor 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 338443 |
| Gene Symbol | Gpbar1 |
| UniProt | Q80T02 (GPBAR_RAT), U5JAP5 (U5JAP5_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
69
Total Number of Articles : 91 |
Description |
G protein-coupled bile acid receptor 1 |
| Gene Summary |
Enables G protein-coupled receptor activity. Involved in positive regulation of ERK1 and ERK2 cascade and positive regulation of cholangiocyte proliferation. Predicted to be located in cytoplasm. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Biomarker of metabolic dysfunction-associated steatohepatitis and polycystic kidney disease. Orthologous to human GPBAR1 (G protein-coupled bile acid receptor 1). [provided by Alliance of Genome Resources, Jun 2025] |
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