Protein Name beta-1,4-N-acetyl-galactosaminyl transferase 1
Organism Mus musculus
Gene ID 14421
Gene Symbol

B4galnt1

UniProt Q09200 (B4GN1_MOUSE), Q3UN35 (Q3UN35_MOUSE), Q8VDF0 (Q8VDF0_MOUSE), A0A1Z4EAV4 (A0A1Z4EAV4_MOUSE)
Relationships Total Number of functionally related compound(s) : 38
Total Number of Articles : 47
Description

beta-1,4-N-acetyl-galactosaminyl transferase 1

Gene Summary

Enables (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity. Involved in ganglioside biosynthetic process. Acts upstream of or within glycosphingolipid metabolic process; lipid storage; and spermatogenesis. Predicted to be located in Golgi membrane and plasma membrane. Is expressed in several structures, including alimentary system; eye; genitourinary system; hemolymphoid system; and nervous system. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 26. Orthologous to human B4GALNT1 (beta-1,4-N-acetyl-galactosaminyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • beta-1,4 N-acetylgalactosaminyltransferase 1
  • (N-acetylneuraminyl)-galactosylglucosylceramide
  • GM2/GD2 synthase
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Properties