Protein Name ST6 beta-galactoside alpha-2,6-sialyltransferase 1
Organism Homo sapiens
Gene ID 6480
Gene Symbol

ST6GAL1

UniProt P15907 (SIAT1_HUMAN)
Relationships Total Number of functionally related compound(s) : 135
Total Number of Articles : 148
Description

ST6 beta-galactoside alpha-2,6-sialyltransferase 1

Gene Summary

This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]

synonyms
  • beta-galactoside alpha-2,6-sialyltransferase 1
  • B-cell antigen CD75
  • CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase
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Properties