| Protein Name | histone deacetylase 5 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 15184 |
| Gene Symbol | Hdac5 |
| UniProt | Q3UJF1 (Q3UJF1_MOUSE), Q6P9T4 (Q6P9T4_MOUSE), B7ZDF7 (B7ZDF7_MOUSE), B7ZDF5 (B7ZDF5_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
68
Total Number of Articles : 59 |
Description |
histone deacetylase 5 |
| Gene Summary |
Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; transcription corepressor activity; and transcription corepressor binding activity. Involved in several processes, including cellular response to fluid shear stress; positive regulation of cell population proliferation; and regulation of myotube differentiation. Acts upstream of or within several processes, including negative regulation of macromolecule biosynthetic process; negative regulation of osteoblast differentiation; and regulation of myotube differentiation. Located in several cellular components, including axonal growth cone; chromatin; and nuclear body. Part of RNA polymerase II transcription repressor complex. Is active in nucleus. Is expressed in several structures, including central nervous system; early embryo; head bone; sensory organ; and upper arm. Orthologous to human HDAC5 (histone deacetylase 5). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |