| Protein Name | TIMP metallopeptidase inhibitor 3 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 7078 |
| Gene Symbol | TIMP3 |
| UniProt | P35625 (TIMP3_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
219
Total Number of Articles : 215 |
Description |
TIMP metallopeptidase inhibitor 3 |
| Gene Summary |
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008] |
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