| Protein Name | src homology 2 domain-containing transforming protein C1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 20416 |
| Gene Symbol | Shc1 |
| UniProt | P98083 (SHC1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
141
Total Number of Articles : 288 |
Description |
src homology 2 domain-containing transforming protein C1 |
| Gene Summary |
Enables epidermal growth factor binding activity; identical protein binding activity; and signaling receptor binding activity. Involved in insulin-like growth factor receptor signaling pathway. Acts upstream of or within several processes, including circulatory system development; epidermal growth factor receptor signaling pathway; and positive regulation of MAPK cascade. Predicted to be located in endosome membrane. Predicted to be part of Shc-EGFR complex. Predicted to be active in plasma membrane. Is expressed in several structures, including cerebral cortex; early conceptus; liver; skeleton; and skin. Orthologous to human SHC1 (SHC adaptor protein 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |