Protein Name luteinizing hormone/choriogonadotropin receptor
Organism Homo sapiens
Gene ID 3973
Gene Symbol


UniProt P22888 (LSHR_HUMAN)
Relationships Total Number of functionally related compound(s) : 210
Total Number of Articles : 325

luteinizing hormone/choriogonadotropin receptor

Gene Summary

This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq, Jul 2008]

  • lutropin-choriogonadotropic hormone receptor
  • hypergonadotropic hypogonadism
  • lutropin/choriogonadotropin receptor
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