| Protein Name | telomerase reverse transcriptase |
|---|---|
| Organism | Mus musculus |
| Gene ID | 21752 |
| Gene Symbol | Tert |
| UniProt | O70372 (TERT_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
120
Total Number of Articles : 107 |
Description |
telomerase reverse transcriptase |
| Gene Summary |
Enables telomerase RNA binding activity; telomerase activity; and transcription coactivator binding activity. Involved in positive regulation of Wnt signaling pathway; positive regulation of hair cycle; and positive regulation of stem cell proliferation. Acts upstream of or within positive regulation of D-glucose import. Located in mitochondrion and plasma membrane. Part of telomerase catalytic core complex. Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system gland; sensory organ; and skin. Used to study prostate cancer. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant dyskeratosis congenita 2; carcinoma (multiple); gastrointestinal stromal tumor; leukemia (multiple); and melanoma (multiple). Orthologous to human TERT (telomerase reverse transcriptase). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |