Protein Name vasohibin 1
Organism Homo sapiens
Gene ID 22846
Gene Symbol

VASH1

UniProt Q7L8A9 (VASH1_HUMAN)
Relationships Total Number of functionally related compound(s) : 27
Total Number of Articles : 23
Description

vasohibin 1

Gene Summary

Enables actin binding activity and metallocarboxypeptidase activity. Involved in negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell migration; and proteolysis. Acts upstream of or within several processes, including negative regulation of endothelial cell proliferation; negative regulation of lymphangiogenesis; and regulation of cellular senescence. Located in apical part of cell; endoplasmic reticulum; and extracellular space. Implicated in liver cirrhosis and portal hypertension. Biomarker of liver cirrhosis. [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • tubulinyl-Tyr carboxypeptidase 1
  • tubulin carboxypeptidase 1
  • tyrosine carboxypeptidase 1
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Properties