| Protein Name | dentin sialophosphoprotein |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25254 |
| Gene Symbol | Dspp |
| UniProt | Q8VBY1 (Q8VBY1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
28
Total Number of Articles : 20 |
Description |
dentin sialophosphoprotein |
| Gene Summary |
Enables collagen binding activity. Involved in several processes, including cellular response to dexamethasone stimulus; mandibular condyle articular cartilage development; and odontoblast differentiation. Acts upstream of or within positive regulation of calcium ion import. Located in extracellular matrix; nucleus; and plasma membrane. Biomarker of osteoporosis. Human ortholog(s) of this gene implicated in dentinogenesis imperfecta. Orthologous to human DSPP (dentin sialophosphoprotein). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |