Protein Name adenosine A2b receptor
Organism Mus musculus
Gene ID 11541
Gene Symbol

Adora2b

UniProt Q60614 (AA2BR_MOUSE)
Relationships Total Number of functionally related compound(s) : 63
Total Number of Articles : 115
Description

adenosine A2b receptor

Gene Summary

Enables G protein-coupled adenosine receptor activity. Involved in G protein-coupled adenosine receptor signaling pathway and presynaptic modulation of chemical synaptic transmission. Acts upstream of or within several processes, including positive regulation of chronic inflammatory response to non-antigenic stimulus; positive regulation of cytokine production; and positive regulation of guanylate cyclase activity. Located in plasma membrane. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including cardiovascular system; central nervous system; eye; genitourinary system; and gut. Orthologous to human ADORA2B (adenosine A2b receptor). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • adenosine receptor A2b
  • A2b, Rs
  • A2BAR
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Properties