Protein Name aryl hydrocarbon receptor nuclear translocator
Organism Mus musculus
Gene ID 11863
Gene Symbol

Arnt

UniProt P53762 (ARNT_MOUSE), Q3ULM2 (Q3ULM2_MOUSE)
Relationships Total Number of functionally related compound(s) : 92
Total Number of Articles : 137
Description

aryl hydrocarbon receptor nuclear translocator

Gene Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; nuclear receptor activity; and protein heterodimerization activity. Involved in positive regulation of protein sumoylation. Acts upstream of or within several processes, including embryonic placenta development; positive regulation of transcription by RNA polymerase II; and response to hypoxia. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human ARNT (aryl hydrocarbon receptor nuclear translocator). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • aryl hydrocarbon receptor nuclear translocator
  • HIF-1-beta
  • HIF1-beta
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Properties