Protein Name | aryl hydrocarbon receptor nuclear translocator |
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Organism | Mus musculus |
Gene ID | 11863 |
Gene Symbol | Arnt |
UniProt | P53762 (ARNT_MOUSE), Q3ULM2 (Q3ULM2_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
92
Total Number of Articles : 137 |
Description |
aryl hydrocarbon receptor nuclear translocator |
Gene Summary |
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; nuclear receptor activity; and protein heterodimerization activity. Involved in positive regulation of protein sumoylation. Acts upstream of or within several processes, including embryonic placenta development; positive regulation of transcription by RNA polymerase II; and response to hypoxia. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human ARNT (aryl hydrocarbon receptor nuclear translocator). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |