Protein Name chibby 1, beta catenin antagonist
Organism Homo sapiens
Gene ID 25776
Gene Symbol

CBY1

UniProt Q9Y3M2 (CBY1_HUMAN), A0A024R1L9 (A0A024R1L9_HUMAN), A0A087WUW0 (A0A087WUW0_HUMAN)
Relationships Total Number of functionally related compound(s) : 13
Total Number of Articles : 13
Description

chibby 1, beta catenin antagonist

Gene Summary

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • protein chibby homolog 1
  • ARPP-binding protein
  • PKD2 interactor, Golgi and endoplasmic reticulum-associated 1
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Properties