Protein Name eukaryotic translation initiation factor 4E binding protein 1
Organism Mus musculus
Gene ID 13685
Gene Symbol

Eif4ebp1

UniProt Q60876 (4EBP1_MOUSE)
Relationships Total Number of functionally related compound(s) : 94
Total Number of Articles : 95
Description

eukaryotic translation initiation factor 4E binding protein 1

Gene Summary

Enables eukaryotic initiation factor 4E binding activity. Involved in IRES-dependent translational initiation of linear mRNA. Acts upstream of or within cellular response to dexamethasone stimulus; insulin receptor signaling pathway; and negative regulation of translational initiation. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in glutamatergic synapse and postsynaptic cytosol. Is expressed in several structures, including central nervous system; oocyte; pancreas tip epithelium; skeletal musculature; and thymus. Orthologous to human EIF4EBP1 (eukaryotic translation initiation factor 4E binding protein 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • eukaryotic translation initiation factor 4E-binding protein 1
  • eIF4E-binding protein 1
  • phosphorylated heat- and acid-stable protein regulated by insulin 1
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Properties