Protein Name transient receptor potential cation channel, subfamily M, member 2
Organism Mus musculus
Gene ID 28240
Gene Symbol

Trpm2

UniProt Q91YD4 (TRPM2_MOUSE), Q3UYE9 (Q3UYE9_MOUSE)
Relationships Total Number of functionally related compound(s) : 123
Total Number of Articles : 116
Description

transient receptor potential cation channel, subfamily M, member 2

Gene Summary

Enables ligand-gated calcium channel activity and manganese ion transmembrane transporter activity. Involved in several processes, including calcium ion transmembrane import into cytosol; cellular response to temperature stimulus; and dendritic cell chemotaxis. Acts upstream of or within manganese ion transport and response to hydroperoxide. Located in cytoplasmic vesicle membrane; lysosomal membrane; and plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human TRPM2 (transient receptor potential cation channel subfamily M member 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • transient receptor potential cation channel subfamily M member 2
  • LTrpC-2
  • long transient receptor potential channel 2
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Properties