Protein Name phosphatidate phosphatase PAH1
Organism Saccharomyces cerevisiae S288C
Gene ID 855201
Gene Symbol

PAH1

UniProt P32567 (PAH1_YEAST)
Relationships Total Number of functionally related compound(s) : 39
Total Number of Articles : 57
Description

phosphatidate phosphatase PAH1

Gene Summary

Enables phosphatidate phosphatase activity and transcription cis-regulatory region binding activity. Involved in several processes, including acylglycerol biosynthetic process; lipid droplet organization; and vacuole fusion, non-autophagic. Located in cytosol; lipid droplet; and vacuole. Is active in nuclear membrane. Used to study lipid metabolism disorder and myoglobinuria. Human ortholog(s) of this gene implicated in chronic recurrent multifocal osteomyelitis. Orthologous to human LPIN1 (lipin 1); LPIN2 (lipin 2); and LPIN3 (lipin 3). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • phosphatidate phosphatase PAH1
  • YMR165C
  • SMP2
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Properties