Protein Name 1-pyrroline-5-carboxylate dehydrogenase
Organism Saccharomyces cerevisiae S288C
Gene ID 856432
Gene Symbol

PUT2

UniProt P07275 (PUT2_YEAST)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 23
Description

1-pyrroline-5-carboxylate dehydrogenase

Gene Summary

Enables L-glutamate gamma-semialdehyde dehydrogenase activity. Involved in L-proline catabolic process to L-glutamate and glutamate biosynthetic process. Located in mitochondrial matrix. Used to study disease of metabolism. Human ortholog(s) of this gene implicated in hyperprolinemia type 2. Orthologous to human ALDH4A1 (aldehyde dehydrogenase 4 family member A1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • 1-pyrroline-5-carboxylate dehydrogenase
  • YHR037W
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Properties