| Protein Name | nei like DNA glycosylase 3 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 55247 |
| Gene Symbol | NEIL3 |
| UniProt | Q8TAT5 (NEIL3_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
34
Total Number of Articles : 24 |
Description |
nei like DNA glycosylase 3 |
| Gene Summary |
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008] |
| synonyms |
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| Properties | |