Protein Name | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
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Organism | Xenopus tropicalis |
Gene ID | 448586 |
Gene Symbol | srd5a1 |
UniProt | Q6DF23 (Q6DF23_XENTR) |
Relationships |
Total Number of functionally related compound(s) :
3
Total Number of Articles : 2 |
Description |
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
Gene Summary |
Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in androgen biosynthetic process and male gonad development. Predicted to act upstream of or within cell differentiation; sex differentiation; and steroid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in neuronal cell body. Is expressed in anatomical system; pharyngeal arch; and primary germ layer. Human ortholog(s) of this gene implicated in alcohol dependence; prostate cancer; and prostatic hypertrophy. Orthologous to human SRD5A1 (steroid 5 alpha-reductase 1). [provided by Alliance of Genome Resources, Jun 2025] |
synonyms |
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Properties | |