Protein Name steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Organism Xenopus tropicalis
Gene ID 448586
Gene Symbol

srd5a1

UniProt Q6DF23 (Q6DF23_XENTR)
Relationships Total Number of functionally related compound(s) : 3
Total Number of Articles : 2
Description

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)

Gene Summary

Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in androgen biosynthetic process and male gonad development. Predicted to act upstream of or within cell differentiation; sex differentiation; and steroid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in neuronal cell body. Is expressed in anatomical system; pharyngeal arch; and primary germ layer. Human ortholog(s) of this gene implicated in alcohol dependence; prostate cancer; and prostatic hypertrophy. Orthologous to human SRD5A1 (steroid 5 alpha-reductase 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • 3-oxo-5-alpha-steroid 4-dehydrogenase 1
  • SRD5alpha1
Click to show/hide the synonyms
Properties