Protein Name proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
Organism Mus musculus
Gene ID 16913
Gene Symbol

Psmb8

UniProt P28063 (PSB8_MOUSE)
Relationships Total Number of functionally related compound(s) : 33
Total Number of Articles : 31
Description

proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)

Gene Summary

Predicted to enable endopeptidase activity. Involved in fat cell differentiation. Acts upstream of or within antigen processing and presentation. Part of proteasome core complex and spermatoproteasome complex. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in proteasome-associated autoinflammatory syndrome 1. Orthologous to human PSMB8 (proteasome 20S subunit beta 8). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • proteasome subunit beta type-8
  • MC13 (LMP7)
  • large multifunctional protease 7
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Properties