Protein Name endonuclease G
Organism Homo sapiens
Gene ID 2021
Gene Symbol

ENDOG

UniProt Q14249 (NUCG_HUMAN), E5KNL5 (E5KNL5_HUMAN)
Relationships Total Number of functionally related compound(s) : 98
Total Number of Articles : 90
Description

endonuclease G

Gene Summary

The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq, Jul 2008]

synonyms
  • endonuclease G, mitochondrial
  • endo G
  • mitochondrial endonuclease G
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Properties