Protein Name A-kinase anchoring protein 11
Organism Homo sapiens
Gene ID 11215
Gene Symbol

AKAP11

UniProt Q9UKA4 (AKA11_HUMAN)
Relationships Total Number of functionally related compound(s) : 12
Total Number of Articles : 10
Description

A-kinase anchoring protein 11

Gene Summary

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008]

synonyms
  • A-kinase anchor protein 11
  • A kinase (PRKA) anchor protein 11
  • A-kinase anchor protein 220 kDa
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Properties