| Protein Name | Von Willebrand factor |
|---|---|
| Organism | Mus musculus |
| Gene ID | 22371 |
| Gene Symbol | Vwf |
| UniProt | Q8CIZ8 (VWF_MOUSE), E9QPU1 (E9QPU1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
124
Total Number of Articles : 136 |
Description |
Von Willebrand factor |
| Gene Summary |
Predicted to enable several functions, including chaperone binding activity; identical protein binding activity; and integrin binding activity. Acts upstream of or within several processes, including liver development; placenta development; and platelet activation. Located in external side of plasma membrane. Is expressed in several structures, including cardiovascular system; extraembryonic component; genitourinary system; leptomeninges; and vitelline blood vessel. Used to study von Willebrand's disease and von Willebrand's disease 2. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; Bernard-Soulier syndrome; end stage renal disease; essential thrombocythemia; and von Willebrand's disease (multiple). Orthologous to human VWF (von Willebrand factor). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |