| Protein Name | sphingomyelin phosphodiesterase 3, neutral |
|---|---|
| Organism | Mus musculus |
| Gene ID | 58994 |
| Gene Symbol | Smpd3 |
| UniProt | Q9JJY3 (NSMA2_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
37
Total Number of Articles : 38 |
Description |
sphingomyelin phosphodiesterase 3, neutral |
| Gene Summary |
Enables identical protein binding activity; neutral sphingomyelin phosphodiesterase activity; and phospholipid binding activity. Involved in sphingomyelin metabolic process. Acts upstream of or within several processes, including animal organ development; enzyme linked receptor protein signaling pathway; and sphingolipid metabolic process. Located in Golgi cis cisterna and plasma membrane. Is expressed in several structures, including alimentary system; limb; nervous system; sensory organ; and skeleton. Used to study hypopituitarism; osteogenesis imperfecta; osteogenesis imperfecta type 2; and osteogenesis imperfecta type 3. Orthologous to human SMPD3 (sphingomyelin phosphodiesterase 3). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |