Protein Name | UDP glucuronosyltransferase 1 family, polypeptide A1 |
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Organism | Mus musculus |
Gene ID | 394436 |
Gene Symbol | Ugt1a1 |
UniProt | Q63886 (UD11_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
79
Total Number of Articles : 81 |
Description |
UDP glucuronosyltransferase 1 family, polypeptide A1 |
Gene Summary |
Predicted to enable several functions, including glucuronosyltransferase activity; protein dimerization activity; and retinoic acid binding activity. Predicted to be involved in several processes, including biphenyl catabolic process; cellular glucuronidation; and negative regulation of cellular glucuronidation. Is integral component of plasma membrane. Part of endoplasmic reticulum chaperone complex. Is expressed in alimentary system; nervous system; and urinary system. Human ortholog(s) of this gene implicated in several diseases, including bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; female reproductive organ cancer (multiple); and hepatitis B. Orthologous to human UGT1A1 (UDP glucuronosyltransferase family 1 member A1). [provided by Alliance of Genome Resources, Apr 2022] |
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