Protein Name alkaline phosphatase, intestinal
Organism Homo sapiens
Gene ID 248
Gene Symbol

ALPI

UniProt P09923 (PPBI_HUMAN), A0A024R4A2 (A0A024R4A2_HUMAN)
Relationships Total Number of functionally related compound(s) : 240
Total Number of Articles : 245
Description

alkaline phosphatase, intestinal

Gene Summary

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is a component of the gut mucosal defense system and is thought to function in the detoxification of lipopolysaccharide, and in the prevention of bacterial translocation in the gut. [provided by RefSeq, Dec 2014]

synonyms
  • intestinal-type alkaline phosphatase
  • Kasahara isozyme
  • alkaline phosphomonoesterase
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Properties