Protein Name ATP binding cassette subfamily C member 4 (PEL blood group)
Organism Homo sapiens
Gene ID 10257
Gene Symbol


UniProt O15439 (MRP4_HUMAN), A8K2Q2 (A8K2Q2_HUMAN)
Relationships Total Number of functionally related compound(s) : 409
Total Number of Articles : 378

ATP binding cassette subfamily C member 4 (PEL blood group)

Gene Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

  • ATP-binding cassette sub-family C member 4
  • MRP/cMOAT-related ABC transporter
  • bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4)
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