CPRiL

ABCC4

ATP binding cassette subfamily C member 4 (PEL blood group)

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

• ATP-binding cassette sub-family C member 4
• MRP/cMOAT-related ABC transporter
• bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4)
canalicular multispecific organic anion transporter (ABC superfamily)
multi-specific organic anion transporter B
multidrug resistance-associated protein 4
MOAT-B
MOATB
MRP4