Protein Name argonaute RISC catalytic component 2
Organism Homo sapiens
Gene ID 27161
Gene Symbol

AGO2

UniProt Q9UKV8 (AGO2_HUMAN)
Relationships Total Number of functionally related compound(s) : 178
Total Number of Articles : 174
Description

argonaute RISC catalytic component 2

Gene Summary

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

synonyms
  • protein argonaute-2
  • PAZ Piwi domain protein
  • argonaute 2, RISC catalytic component
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Properties