| Protein Name | Histone deacetylase 1 |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 38565 |
| Gene Symbol | HDAC1 |
| UniProt | Q94517 (HDAC1_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
12
Total Number of Articles : 11 |
Description |
Histone deacetylase 1 |
| Gene Summary |
Enables histone H4K deacetylase activity and transcription corepressor activity. Involved in several processes, including determination of adult lifespan; negative regulation of macromolecule biosynthetic process; and negative regulation of response to gamma radiation. Located in chromatin; nucleus; and polytene chromosome interband. Part of Myb complex; nucleoplasm; and transcription repressor complex. Is expressed in several structures, including Malpighian tubule primordium; embryonic/larval midgut primordium; ganglia; gonad; and imaginal disc. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to several human genes including HDAC2 (histone deacetylase 2). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |