Protein Name sirtuin 7
Organism Mus musculus
Gene ID 209011
Gene Symbol

Sirt7

UniProt Q8BKJ9 (SIR7_MOUSE)
Relationships Total Number of functionally related compound(s) : 22
Total Number of Articles : 26
Description

sirtuin 7

Gene Summary

Enables NAD-dependent protein-lysine depropionylase activity and histone H3K18 deacetylase activity, NAD-dependent. Involved in several processes, including chromatin remodeling; homologous chromosome pairing at meiosis; and protein deacylation. Located in chromatin and site of double-strand break. Is expressed in several structures, including 1st branchial arch maxillary component; central nervous system; eye; gonad; and pancreas. Orthologous to human SIRT7 (sirtuin 7). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • NAD-dependent protein deacetylase sirtuin-7
  • NAD-dependent deacetylase sirtuin-7
  • NAD-dependent protein deacylase sirtuin-7
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Properties