| Protein Name | crumbs cell polarity complex component 2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 286204 |
| Gene Symbol | CRB2 |
| UniProt | Q5IJ48 (CRUM2_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
13
Total Number of Articles : 17 |
Description |
crumbs cell polarity complex component 2 |
| Gene Summary |
This gene encodes a member of a family of proteins that are components of the Crumbs cell polarity complex. In mammals, members of this family are thought to play a role in many cellular processes in early embryonic development. A similar protein in Drosophila determines apicobasal polarity in embryonic epithelial cells. Mutations in this gene are associated with focal segmental glomerulosclerosis 9, and with ventriculomegaly with cystic kidney disease. [provided by RefSeq, Aug 2016] |
| synonyms |
|
| Properties | |