| Protein Name | avian reticuloendotheliosis viral (v-rel) oncogene related B |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19698 |
| Gene Symbol | Relb |
| UniProt | Q04863 (RELB_MOUSE), Q8K220 (Q8K220_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
44
Total Number of Articles : 41 |
Description |
avian reticuloendotheliosis viral (v-rel) oncogene related B |
| Gene Summary |
Enables DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in circadian regulation of gene expression; negative regulation of DNA-templated transcription; and non-canonical NF-kappaB signal transduction. Acts upstream of or within T-helper 1 cell differentiation; antigen processing and presentation; and myeloid dendritic cell differentiation. Located in cytosol and nucleus. Is active in synapse. Is expressed in several structures, including central nervous system; genitourinary system; gut; liver; and lung. Used to study atopic dermatitis. Human ortholog(s) of this gene implicated in breast cancer and immunodeficiency 53. Orthologous to human RELB (RELB proto-oncogene, NF-kB subunit). [provided by Alliance of Genome Resources, Jul 2025] |
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